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Author

Dr. Gaurang Ramesh

Date

July 16, 2023

Dear readers!

As a Gastrointestinal Surgeon integrating functional and conventional gastroenterology in India, I often encounter patients who wrestle with more than just physical discomfort. A significant number of them grapple with mental health issues, particularly depression and anxiety, and it’s impossible to ignore the intricate link between our minds and our bodies.
Today, I’d like to talk about the root causes of these mental health conditions and how functional medicine can offer a holistic and integrative approach to address them.

Understanding Depression and Anxiety Through the Functional Medicine Lens

Depression and anxiety are no longer viewed solely as psychological disorders. They are multi-factorial conditions that encompass our whole being – mind, body, and soul.
Functional medicine, with its holistic and patient-centered approach, tries to unravel the underlying causes of these mental health conditions rather than merely managing the symptoms. This approach focuses on the ‘why’ instead of the ‘what’ – which means instead of asking, “What antidepressants should we prescribe?”, functional medicine asks, “Why is this patient feeling depressed?”

The Gut-Brain Axis: The Heart of the Matter

Emerging research shows a profound connection between our gut health and our mental wellbeing. This is referred to as the gut-brain axis. Our gastrointestinal system houses trillions of microbes (collectively known as the gut microbiota) that communicate with our brain through various pathways. Any imbalance in this gut microbiota can lead to a cascade of reactions impacting mental health.
Depression and anxiety, surprisingly, can be tied back to our gut health. As a practitioner of both conventional gastroenterology and functional medicine, I’ve seen firsthand the transformative effects of gut healing on mental wellbeing.

Root Causes: Beyond Just Genetics

Depression and anxiety cannot be simplistically attributed to genetics. They are also heavily influenced by lifestyle factors such as diet, sleep, physical activity, and stress levels. Functional medicine digs deep into these factors, seeking to correct imbalances and restore health.
For example, our modern diet, typically high in processed foods and low in fiber and fermented foods, can negatively impact our gut microbiota, leading to a chain reaction affecting our mood and mental health. By optimizing the diet, we can restore gut balance and, consequently, improve mental health conditions.

Mitochondrial Dysfunction: A Silent Culprit in Depression and Anxiety

In our discussion of depression and anxiety, it’s critical we explore the significant, often overlooked role of cellular health, specifically our mitochondria. These tiny powerhouses within each cell generate about 90% of the energy our body needs to function properly. But what happens when they don’t work as they should?
Mitochondrial dysfunction refers to a situation where the mitochondria are not efficiently producing energy, either due to genetic mutations, environmental factors, or lifestyle behaviors. This impairment can impact every cell, tissue, and organ in the body, including the brain, leading to various health problems.
Depression and anxiety are now being linked with mitochondrial dysfunction. The brain, being an energy-demanding organ, is particularly susceptible to changes in mitochondrial function. If the brain cells aren’t provided with the energy they need, it can lead to altered brain function and contribute to mental health conditions like depression and anxiety.
Scientific studies have shown altered mitochondrial function in the brains of patients suffering from these conditions. These alterations may impact various aspects of brain health, including neurotransmitter regulation, neural plasticity, and stress responses, all of which play significant roles in mental health.
Functional medicine sees mitochondrial health as a cornerstone of overall wellbeing. By addressing lifestyle factors such as diet, sleep, and exercise, which can all influence mitochondrial function, we can help restore cellular health.
Certain nutritional supplements, including Coenzyme Q10, L-carnitine, and certain B vitamins, are also being explored for their potential to support mitochondrial health and may be incorporated into an individualized treatment plan based on a person’s specific needs.
Mitochondrial health and resilience, therefore, form an essential part of our integrative approach to managing depression and anxiety. Recognizing and addressing mitochondrial dysfunction allows us to treat these conditions from their very roots, offering hope for long-lasting relief and improved quality of life.

The Integrative Approach: A Symphony of Healt

Functional medicine is integrative and personalized. In addition to diet modifications, it might include stress management techniques like meditation, yoga, or mindfulness practices. Regular physical activity and good sleep hygiene are also essential pillars of this approach.
Sometimes, supplementing with specific nutrients or using certain medications might be necessary to correct imbalances or deficiencies. All of these strategies are tailored to the individual patient’s needs and circumstances.

Depression and anxiety are complex conditions that require an integrated, holistic approach for effective management. Functional medicine, with its focus on identifying and treating the root causes, provides an excellent framework to tackle these disorders.
As we continue to embrace functional medicine, my hope is for us to create a world where mental health is seen and treated as a part of our overall health, rather than a separate entity. It is time to look beyond conventional methods and towards a future that offers comprehensive, compassionate, and personalized care for all.
In my upcoming blogs, I’ll be sharing more about the role of gut health in various chronic conditions and how functional medicine can help. Stay tuned!
Remember, every journey towards wellness starts with one small, conscious step. Take that step today, and let’s walk this path together.

BLOGS

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