Ozone Therapy at Wellness Retreats: Trend or Evidence-Based?

Published on: 9/Aug/2025
Posted By: Arka Health

Introduction: The Rise of Ozone Therapy in the Wellness World

In the ever-expanding universe of health and wellness, new trends emerge at lightning speed. From biohacking technologies to ancient healing practices, the modern wellness retreat offers a dazzling menu of options for rejuvenation. One of the most talked-about treatments now appearing in luxury spas and holistic healing centres across India is ozone therapy

Promoted as a powerful tool for detoxification, anti-aging, and boosting immunity, ozone therapy has become a popular feature in wellness packages. This has led many health-conscious individuals in cities like Bengaluru to ask a critical question: Is ozone therapy at wellness retreats a legitimate, evidence-based treatment, or is it just a fleeting wellness trend?

The answer is complex. While the therapy itself is rooted in over a century of medical application, its effectiveness and, more importantly, its safety, are entirely dependent on the context in which it is administered. At Arka Anugraha Hospital (Arka Health), a leading centre for integrative and functional medicine in JP Nagar, South Bengaluru, we believe in separating the science from the spa day. This guide will explore the evidence behind medical spa ozone therapy and clarify the crucial differences between receiving treatment at a wellness retreat versus a dedicated medical clinic.

What is Ozone Therapy and Why is it Popular at Wellness Retreats?

Medical ozone therapy is a procedure that uses a precise mixture of pure, medical-grade oxygen and ozone (a supercharged form of oxygen) to stimulate the body’s natural healing mechanisms. It’s not a new-age fad; its therapeutic use dates back to the early 1900s for disinfecting wounds. ,

Its recent surge in popularity within the wellness industry is driven by its alignment with the core goals of a modern health retreat: detoxification, rejuvenation, and performance enhancement. The global wellness economy is a trillion-dollar industry, with consumers increasingly demanding science-backed solutions for self-care. Ozone therapy fits this demand perfectly, with proponents claiming it can:

  • Enhance Detoxification: Support the body in eliminating toxins and heavy metals. 
  • Boost the Immune System: Modulate and strengthen the body’s defences against pathogens.
  • Promote Anti-Aging: Improve skin health and cellular vitality. 
  • Increase Energy Levels: Improve oxygen metabolism and cellular energy production. 

At wellness retreats, you might find ozone therapy offered in several appealing forms, such as relaxing ozone saunas, ozonated water for drinking, or intravenous (IV) infusions promising a full-body reset. 

Separating Hype from Health: The Evidence Behind the Claims

While the claims made at some wellness retreats can sound miraculous, it’s important to look at the evidence for ozone therapy. Decades of research have shown that when administered correctly, medical ozone can produce measurable biological effects that support these wellness goals.

Fact: Ozone Therapy Supports Cellular Detoxification

One of the most well-documented benefits is its ability to enhance the body’s natural detoxification processes. It works by activating a key cellular pathway called Nrf2, which acts as a master switch for the body’s antioxidant response. 7 This leads to a significant increase in the production of glutathione, the body’s most powerful antioxidant and detoxifying agent.

Studies have also shown that ozone therapy can improve liver blood flow by up to 70% and lead to a 20-30% improvement in liver enzyme measurements, enhancing the organ’s ability to process and eliminate toxins. 

Fact: It Is a Powerful Immune Modulator

Ozone therapy doesn’t just “boost” the immune system; it intelligently modulates it. Research shows it can stimulate the production and activity of key immune cells, including T-lymphocytes and natural killer cells, making the body more efficient at fighting off bacteria, viruses, and fungi.  This makes it a valuable supportive therapy for those with compromised immunity or chronic infections. 

Fact: It Has Proven Anti-Aging and Skin Rejuvenation Effects

The anti-aging benefits are not just skin deep. Ozone therapy stimulates fibroblasts, the cells responsible for producing collagen and elastin, which are essential for skin firmness and elasticity.  By improving microcirculation, it delivers more oxygen and nutrients to the skin cells, resulting in a more vibrant complexion and a reduction in fine lines.

Fact: It Enhances Energy and Vitality

By improving the ability of red blood cells to deliver oxygen to tissues and enhancing mitochondrial function, ozone therapy can boost cellular energy (ATP) production. This translates to improved physical performance, reduced fatigue, and an overall feeling of well-being. 

The Critical Difference: Wellness Retreat vs. Medical Clinic

While the evidence for ozone therapy is compelling, its safety and effectiveness are entirely dependent on how and where it is administered. This is where the distinction between a wellness retreat and a dedicated medical clinic becomes crucial.

The Setting and Supervision

A wellness retreat is designed for relaxation and rejuvenation. While enjoyable, it is often not a medical environment. A medical clinic or hospital, like Arka Health, operates under strict clinical protocols with direct medical supervision.  This is non-negotiable for a procedure that involves administering a powerful medical gas.

Practitioner Qualifications

The person administering your therapy matters most. In a spa or retreat setting, the staff may not be medically qualified. In India, credible ozone therapy is performed by trained medical doctors (MBBS) who have undergone specialized certification, often through organizations like the Ozone Forum of India.  This ensures they understand the complex biochemistry, appropriate dosages, and contraindications.

Safety Protocols and Dosage

Medical ozone therapy is a science of precision. Too low a dose may be ineffective, while too high a dose can be toxic. Reputable medical clinics adhere to internationally recognized safety standards, such as the Madrid Declaration on Ozone Therapy, which outlines precise therapeutic concentrations and safe administration methods based on thousands of scientific papers.  A wellness retreat may not use medical-grade ozone generators or follow these strict protocols, increasing the risk of adverse effects.

Medical Assessment and Personalization

A crucial part of safe ozone therapy is a thorough initial medical consultation. A qualified doctor will review your medical history and screen for contraindications like pregnancy, G6PD deficiency, or uncontrolled hyperthyroidism. The treatment plan is then tailored to your specific health needs. This level of personalized medical care is the standard in a functional medicine clinic but is often absent in a one-size-fits-all retreat setting.

Risks of Ozone Therapy in Non-Clinical Settings

When protocols are not followed, or when the therapy is administered by untrained individuals, ozone therapy can be dangerous.

  • Inhalation Risk: The cardinal rule of ozone therapy is that it must never be inhaled. Ozone gas is a powerful oxidant that can cause severe irritation and damage to the lungs.  In a non-clinical setting, the risk of accidental leakage and inhalation is higher.
  • Risk of Air Embolism: Outdated and dangerous techniques like the direct intravenous injection of ozone gas can cause a fatal air embolism. Certified clinics use safe methods like Major Autohemotherapy, where blood is ozonated outside the body in a sterile, closed system.
  • Infection and Contamination: Any invasive procedure carries a risk of infection. A sterile, clinical environment is essential to mitigate this risk.

Finding Evidence-Based Ozone Therapy in Bengaluru

The growing interest in integrative medicine in Bengaluru means there are more options than ever. To ensure you are choosing a safe and effective provider, look for:

  1. A Clinical Setting: The therapy should be offered in a hospital or a dedicated medical clinic.
  2. A Qualified Doctor: Ensure the practitioner is a licensed medical doctor (MBBS) with specific training and certification in ozone therapy. 
  3. A Comprehensive Approach: A good provider will conduct a thorough assessment and integrate the therapy into a holistic, personalized health plan. 

At Arka Health, we meet and exceed these standards. As India’s only dedicated centre offering advanced functional medicine and holistic wellness solutions within a multi-specialty hospital, we provide a unique and safe environment for therapies like ozone. Our founder, Dr. Gaurang Ramesh, is an expert in integrative medicine, ensuring that your treatment is not just a procedure, but part of a comprehensive strategy to address the root cause of your health concerns.

Conclusion: Choose Science-Backed Wellness, Not Just a Trend

Ozone therapy is far more than a passing wellness trend. It is an evidence-based medical treatment with a long history and a growing body of scientific support for its benefits in detoxification, immune support, and rejuvenation. However, its power comes with a responsibility.

The luxurious setting of a wellness retreat may be appealing, but when it comes to your health, the expertise, safety, and personalization of a clinical environment are non-negotiable. By choosing a medical facility like Arka Health, you ensure that you are receiving a therapy that is not only effective but, most importantly, safe.

Don’t settle for a trend when you can have evidence-based care. Book a consultation at Arka Health in JP Nagar, Bengaluru, to explore how ozone therapy can be a safe and powerful part of your personalized wellness journey.

Frequently Asked Questions (FAQ)

Is ozone therapy just a wellness fad?

No, ozone therapy has been used in medicine for over 100 years and is supported by a large body of scientific research. 4 Its recent popularity in wellness is a trend, but the therapy itself is an established medical procedure when performed correctly.

Is it safe to get ozone therapy at a spa or retreat?

It carries significant risks. The safety of ozone therapy depends on medical supervision, the use of medical-grade equipment, precise dosing, and administration by trained doctors.  These standards are most reliably met in a clinical or hospital setting, not a spa.

What qualifications should an ozone therapy provider in India have?

A provider should be a qualified medical doctor (MBBS) and ideally hold a certification from a recognized professional body like the Ozone Forum of India, which provides training based on international protocols.

How is medical ozone therapy different from ozone air purifiers?

They are completely different and should not be confused. Medical ozone is a precise gas mixture administered via specific, non-respiratory routes. Ozone from air purifiers is released into the air and is toxic and harmful to the lungs if inhaled.

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